Clínica Odontológica

Instituto de Referencia de Patología Oral

Material de interés

Trabajos de investigación y publicaciones

Rev Med Chil 2003 Jan; 131(1): 60-6
A retrospective study of 232 cases of lip cancer and pre cancer in Chilean patients. Clinical-histological correlation
Ochsenius G, Ormeno A, Godoy L, Rojas R.

Facultad de Odontologia, Instituto de Referencia de Patologia, Oral, Universidad de Chile.

BACKGROUND: The most common type of oral cancer is squamous cell carcinoma, which accounts for approximately 90% of all oral malignancies. Therefore the oral cancer problem primarily concerns the diagnosis, biology and management of squamous cell carcinoma (SCC). However, there are red and white lesions, that are considered premalignant, since they may unpredictably transform into cancer. According to WHO, leukoplakia, eritroplakia and actinic cheilitis are considered precancerous lesions which pathologically may correspond to intraepithelial dysplasia, hyperkeratosis, carcinoma in situ or SCC. AIM: To study the clinical and pathological features of lip cancer and premalignant lip lesions.

PATIENTS AND METHODS: A retrospective analysis of 232 cases with lip lesions. The frequency, location, gender, age and pathological diagnosis of the lesions were recorded.

RESULTS: One hundred fifty four lesions were observed in men and 78 in women, 92% of lesions were located in the lower lip. Seventy two of the 232 lesions were SCC and 72% of these carcinomas were well differentiated. The age of patients with cancer was higher than that of patients with precancerous lesions.

The difference in age between patients with cancer and precancerous lesions, reinforces the existing knowledge that precancerous lesions may transform into cancer if they are not properly diagnosed and treated.


Odontogenic tumors in Chile: a study of 362 cases.
Ochsenius G, Ortega A, Godoy L, Penafiel C, Escobar E.

Oral Pathology Referral Institute, Faculty of Odontology, University of Chile, Santiago, Chile.

BACKGROUND: Odontogenic tumors are infrequent lesions. Thus, the review of a large number of cases becomes a necessity for both the pathologist and the clinician. Studies on odontogenic tumors have been published in many parts of the world, but there is little information available in the English language literature on the relative frequency of odontogenic tumors in Latin America. The aim of this study was to determine the relative frequency of this heterogeneous group of lesions in a Chilean population, and to compare these data with previous reports.

METHODS: We reviewed the records of 28,041 specimens from 1975 to 2000 in the Oral Pathology Referral Institute (IREPO), and using the criteria for histological typification published by the World Health Organization in 1992, we reclassified the odontogenic tumors.

RESULTS: We confirmed a total of 362 odontogenic tumors. The frequency of odontogenic tumors as a percentage of all pathological specimens in our institute was 1.29%. The most frequent histological type was odontomas (44.7%), followed by ameloblastomas (20.4%) and myxomas (8.8%).

CONCLUSIONS: Odontogenic tumors are uncommon lesions in the Chilean population and malignant odontogenic tumors are very rare. The relative frequency of various types of odontogenic tumors, as well as the age and gender distribution are similar to those reported in the North American series and different from those found in recently published Asian and African series.

La base de datos del IREPO ha permitido la realización de varios trabajos de investigación para la titulación de Cirujanos Dentistas. También ha aportado información para alumnos nacionales y extranjeros de Cursos de Especialidades y Magísteres.



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